Quick Read
- Serena Williams revealed her use of GLP-1 weight-loss medications.
- She has lost 31 pounds since starting the medication nearly a year ago.
- Williams partners with Ro to normalize the use of these drugs.
- The medications have improved her physical health and mental well-being.
- She hopes to combat the stigma surrounding weight-loss medications.
Serena Williams, a name synonymous with athletic excellence and resilience, has embarked on a new journey — one that aims to redefine societal perceptions around health and weight management. On August 21, 2025, the 23-time Grand Slam champion disclosed her use of GLP-1 medications to aid in weight loss, a decision she describes as transformative, both physically and mentally. Partnering with telehealth company Ro, Williams is now the face of a campaign to normalize the use of these medications, which are often stigmatized as an ‘easy way out.’
A Journey Rooted in Personal Struggles
Williams’ challenges with weight began in 2017, after the birth of her first daughter, Olympia, via an emergency C-section. Despite her rigorous training as a professional athlete, she struggled to achieve her pre-pregnancy weight. ‘I literally was playing a professional sport, and I could never go back to where I needed to be for my health,’ Williams shared in an interview with Today. The challenges compounded after the birth of her second daughter, Adira, in 2023. No amount of running, walking, or even adopting vegan and high-protein diets seemed to yield the desired results.
Faced with mounting frustration and health concerns, including a family history of diabetes, Williams decided to explore alternative options. After extensive research and consultations, she began taking GLP-1 medications nearly a year ago. ‘I had to make a decision for my life. Do I want to choose health? What do I want to do?’ she reflected.
What Are GLP-1 Medications?
GLP-1 drugs, or glucagon-like peptide-1 receptor agonists, mimic a hormone that helps regulate appetite and blood sugar levels. Initially developed to treat diabetes, these medications are now also prescribed for weight loss. They work by reducing appetite, slowing stomach emptying, and promoting a feeling of fullness. Common brands include Ozempic, Wegovy, and Mounjaro.
According to a report by Reuters, these medications are gaining popularity but remain controversial. Critics argue that they may encourage reliance on pharmaceuticals over lifestyle changes, while proponents highlight their efficacy for individuals who struggle with weight due to genetic or medical factors.
Breaking the Stigma
One of the main goals of Williams’ partnership with Ro is to dismantle the stigma surrounding weight-loss medications. ‘A misconception is that it’s a shortcut,’ she told The Cut. ‘As an athlete, I don’t take shortcuts. I tried everything, and this was the solution that worked for me.’
Williams acknowledges the societal pressure and judgment that often accompanies discussions about weight and health. ‘A lot of people are actually on GLP-1s but don’t want to talk about it,’ she said. Her openness aims to inspire others to prioritize their health without fear of criticism. ‘I feel like my story is so important because I’m so active.’
Her husband, Reddit co-founder Alexis Ohanian, also supports her mission. As an investor in Ro and a member of its board, Ohanian has been instrumental in amplifying the campaign’s reach.
Transformative Results
Since starting the medication, Williams has lost 31 pounds and experienced significant health improvements. ‘My joints feel lighter, like they’re not taking as much of a load,’ she revealed. Her blood sugar levels have normalized, alleviating concerns about diabetes. ‘I just feel normal again,’ she shared with Page Six, adding that she plans to continue using the medication long-term.
Beyond the physical changes, Williams emphasizes the mental and emotional benefits. ‘I feel light physically and light mentally,’ she said. The transformation has also reinvigorated her passion for fitness, as evidenced by her recent social media posts showcasing her toned physique and active lifestyle.
A Broader Conversation
Williams’ advocacy comes at a time when GLP-1 medications are becoming more mainstream. A poll by the nonprofit KFF found that approximately 1 in 8 adults have used these drugs. However, their rising popularity has sparked debates about accessibility and ethical prescribing practices.
By sharing her journey, Williams hopes to contribute to a more informed and empathetic dialogue. ‘This is about choosing health,’ she said. ‘It’s not about taking shortcuts; it’s about finding what works for you.’
As Serena Williams continues to inspire on and off the court, her openness about her health journey serves as a reminder that even icons face challenges — and that seeking solutions is a sign of strength, not weakness.