Recent research has sparked debate about the relationship between vegetarian diets, vitamin B12 levels, and stroke risk. While vegetarian diets are often lauded for their health benefits, some studies suggest that vegetarians may face a higher risk of stroke compared to meat-eaters according to NutritionFacts.org. This seemingly paradoxical finding has prompted further investigation into the potential role of vitamin B12.
The sources explain that vitamin B12, primarily found in animal products, plays a crucial role in maintaining cardiovascular health. When B12 levels are insufficient, the body can experience a buildup of homocysteine, an amino acid linked to an increased risk of stroke and heart disease. Vegetarians and vegans, who exclude meat and other animal products from their diets, are particularly susceptible to B12 deficiency.
However, the sources also caution against relying solely on standard blood tests to assess B12 status. While these tests measure serum B12 levels, the amount of B12 circulating in the blood, they may not accurately reflect the body’s ability to utilize this vitamin effectively. This means individuals can have seemingly normal B12 blood levels while still experiencing a functional B12 deficiency.
Functional B12 deficiency occurs when the body has enough B12 present but cannot use it properly. This can lead to elevated homocysteine levels and increase the risk of stroke, even if blood test results appear normal. The sources suggest that a more reliable indicator of B12 status is measuring methylmalonic acid (MMA) levels in the urine. Elevated MMA is a specific marker of B12 deficiency and can reveal a problem even when serum B12 levels are within the normal range.
To address this concern, the sources recommend that vegetarians and vegans regularly monitor their B12 status, focusing on MMA levels rather than solely relying on serum B12 blood tests. Additionally, they suggest incorporating B12 supplements into their diets to ensure adequate intake and mitigate the risk of stroke associated with deficiency. By taking these precautions, individuals following plant-based diets can reap the numerous health benefits of vegetarianism while minimizing potential risks related to B12.

