In the latest season of Diablo 4, Blizzard has introduced Legacy Runes, a feature inspired by the classic mechanics of Diablo 2. These items are central to creating Runewords, which significantly alter character builds. According to Mobalytics, players can manage their rune inventory by upgrading lower-tier runes into higher-tier versions using the in-game cube system.
However, the system is not universal. Not every rune currently available in the game can be upgraded via the cube. A notable gap in the crafting progression prevents players from creating the Mal rune through standard transmutation methods. This limitation requires players to prioritize farming specific content where the Mal rune drops naturally, rather than relying on cube upgrades for high-level progression.
For those looking to optimize their gear, understanding these crafting recipes is essential for resource management. Players should consult the full list of available transmutation recipes to determine which runes are eligible for upgrading and which must be acquired as loot drops. This distinction is critical for players focusing on end-game builds that require specific high-level Runewords.

